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IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein.

The IRA1 gene is a negative regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae. To identify other genes involved in this pathway, we screened yeast genomic DNA libraries for genes that can suppress the heat shock sensitivity of the ira1 mutation on a multicopy vector. We identified...

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Publicado en:Mol Cell Biol
Autores principales: Tanaka, K, Nakafuku, M, Tamanoi, F, Kaziro, Y, Matsumoto, K, Toh-e, A
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1990
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360976/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164637/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.8.4303-4313.1990
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