Epidermal growth factor stimulation of stromelysin mRNA in rat fibroblasts requires induction of proto-oncogenes c-fos and c-jun and activation of protein kinase C.

Stromelysin (transin) is a secreted metalloprotease that is transcriptionally induced by a variety of growth factors and oncogenes. We examined the necessity of specific secondary (protein kinase C) and tertiary (c-fos and c-jun protein products) messengers in the transactivation of stromelysin gene...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	McDonnell, S E, Kerr, L D, Matrisian, L M
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1990
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360972/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2115124/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.8.4284-4293.1990
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