Multifunctional hybrid silica nanoparticles for controlled doxorubicin loading and release with thermal and pH dually response

Controlled drug loading and release into tumor cells to increase the intracellular drug concentration is a major challenge for cancer therapy due to resistance and inefficient cellular uptake. Here a temperature and pH dually responsive PNiPAM/AA@SiO(2) core-shell particles with internal controlled...

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Detalhes bibliográficos
Main Authors: Hu, Xixue, Hao, Xiaohong, Wu, Yan, Zhang, Jinchao, Zhang, Xiaoning, Wang, Paul C, Zou, Guozhang, Liang, Xing-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609667/
https://ncbi.nlm.nih.gov/pubmed/23543911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2TB00223J
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