Multifunctional hybrid silica nanoparticles for controlled doxorubicin loading and release with thermal and pH dually response

Controlled drug loading and release into tumor cells to increase the intracellular drug concentration is a major challenge for cancer therapy due to resistance and inefficient cellular uptake. Here a temperature and pH dually responsive PNiPAM/AA@SiO(2) core-shell particles with internal controlled...

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Bibliographic Details
Main Authors: Hu, Xixue, Hao, Xiaohong, Wu, Yan, Zhang, Jinchao, Zhang, Xiaoning, Wang, Paul C, Zou, Guozhang, Liang, Xing-Jie
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609667/
https://ncbi.nlm.nih.gov/pubmed/23543911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2TB00223J
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