S-Nitrosation Mediates Multiple Pathways That Lead to Tumor Progression in Estrogen Receptor–Negative Breast Cancer

Chronic inflammation within the tumor microenvironment is a major driver of tumor progression and poor prognosis. Inducible nitric oxide synthase (NOS2) is present in numerous solid tumors. Estrogen receptor–negative (ER−) patients with high expression of tumor NOS2 have a poorer outcome than patien...

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Main Authors: Switzer, Christopher H., Ridnour, Lisa A., Cheng, Robert, Heinecke, Julie, Burke, Amy, Glynn, Sharon, Ambs, Stefan, Wink, David A.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609660/
https://ncbi.nlm.nih.gov/pubmed/23543871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1615/ForumImmunDisTher.2012006108
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