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Basal-like breast cancer stem cells are sensitive to anti-DR5 mediated cytotoxicity

Breast cancer stem cells (BrCSC) are resistant to common therapeutic modalities including chemotherapy, radiation, and hormonal agents. They are thought to contribute to treatment resistance, relapse, and metastases. This study examines the effect of a monoclonal anti-DR5 antibody (TRA-8) and chemot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Londoño-Joshi, Angelina I., Oliver, Patsy G., Li, Yufeng, Lee, Choo Hyung, Forero-Torres, Andres, LoBuglio, Albert F., Buchsbaum, Donald J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609658/
https://ncbi.nlm.nih.gov/pubmed/21915634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1763-0
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