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Basal-like breast cancer stem cells are sensitive to anti-DR5 mediated cytotoxicity

Breast cancer stem cells (BrCSC) are resistant to common therapeutic modalities including chemotherapy, radiation, and hormonal agents. They are thought to contribute to treatment resistance, relapse, and metastases. This study examines the effect of a monoclonal anti-DR5 antibody (TRA-8) and chemot...

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Autori principali: Londoño-Joshi, Angelina I., Oliver, Patsy G., Li, Yufeng, Lee, Choo Hyung, Forero-Torres, Andres, LoBuglio, Albert F., Buchsbaum, Donald J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609658/
https://ncbi.nlm.nih.gov/pubmed/21915634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1763-0
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