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Gap Junction Inhibition Prevents Drug-induced Liver Toxicity and Fulminant Hepatic Failure

Drug-induced liver injury (DILI) limits the development and utilization of numerous therapeutic compounds, and consequently presents major challenges to the pharmaceutical industry and clinical medicine(1, 2). Acetaminophen (APAP) containing compounds are among the most frequently prescribed drugs,...

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Detalhes bibliográficos
Main Authors: Patel, Suraj J, Milwid, Jack M, King, Kevin R, Bohr, Stefan, Iracheta, Arvin, Li, Matthew, Vitalo, Antonia, Parekkadan, Biju, Jindal, Rohit, Yarmush, Martin L
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609650/
https://ncbi.nlm.nih.gov/pubmed/22252509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2089
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