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Axl-dependent signaling: A clinical update
Axl is a receptor tyrosine kinase that was originally cloned from cancer cells. Axl belongs to a TAM (Tyro3, Axl and Mertk) family of receptor tyrosine kinases. Growth arrest specific gene 6 (Gas6) is a ligand for Axl. Activation of Axl protects cells from apoptosis, increases migration, aggregation...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609429/ https://ncbi.nlm.nih.gov/pubmed/22187964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20110411 |
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