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Differentiation of human adipocytes at physiological oxygen levels results in increased adiponectin secretion and isoproterenol-stimulated lipolysis

Adipose tissue (AT) hypoxia occurs in obese humans and mice. Acute hypoxia in adipocytes causes dysregulation of adipokine secretion with an increase in inflammatory factors and diminished adiponectin release. O(2) levels in humans range between 3 and 11% revealing that conventional in vitro culturi...

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Detalhes bibliográficos
Main Authors: Famulla, Susanne, Schlich, Raphaela, Sell, Henrike, Eckel, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609092/
https://ncbi.nlm.nih.gov/pubmed/23700522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adip.19962
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