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Prion formation by a yeast GLFG nucleoporin

The self-assembly of proteins into higher order structures is both central to normal biology and a dominant force in disease. Certain glutamine/asparagine (Q/N)-rich proteins in the budding yeast Saccharomyces cerevisiae assemble into self-replicating amyloid-like protein polymers, or prions, that a...

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Detalhes bibliográficos
Main Authors: Halfmann, Randal, Wright, Jessica R., Alberti, Simon, Lindquist, Susan, Rexach, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609069/
https://ncbi.nlm.nih.gov/pubmed/22561191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.20199
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