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Copy number variation prevalence in known asthma genes and their impact on asthma susceptibility

BACKGROUND: Genetic studies have identified numerous genes reproducibly associated with asthma, yet these studies have focused almost entirely on single nucleotide polymorphisms (SNPs), and virtually ignored another highly prevalent form of genetic variation: Copy Number Variants (CNVs). OBJECTIVE:...

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Hlavní autoři: Rogers, Angela J., Chu, Jen-Hwa, Darvishi, Katayoon, Ionita-Laza, Iuliana, Lehmann, Hillel, Mills, Ryan, Lee, Charles, Raby, Benjamin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609036/
https://ncbi.nlm.nih.gov/pubmed/23517041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12060
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