Excision of N-myc from chromosome 2 in human neuroblastoma cells containing amplified N-myc sequences.
Amplification of one of three growth-stimulating myc genes is a common method by which many tumor types gain a proliferative advantage. In metastatic human neuroblastoma, the amplification of the N-myc locus, located on chromosome 2, is a dominant feature of this usually fatal pediatric cancer. Of t...
Guardat en:
| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1990
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360884/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2405257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.2.823-829.1990 |
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