Myeloid derived suppressor cells regulate growth of multiple myeloma by inhibiting T cells in bone marrow

Myeloid-derived suppressor cells (MDSC) are one of the major factors limiting immune response in cancer. However, their role in bone marrow (BM), the site of primary localization of multiple myeloma (MM), is poorly understood. In this study we found a significant accumulation of CD11b(+)CD14(−)CD33(...

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Main Authors: Ramachandran, Indu, Martner, Anna, Pisklakova, Alexandra, Condamine, Thomas, Chase, Tess, Vogl, Thomas, Roth, Johannes, Gabrilovich, Dmitry, Nefedova, Yulia
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608837/
https://ncbi.nlm.nih.gov/pubmed/23460744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203373
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