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Blocking properdin, the alternative pathway and anaphylatoxin receptors ameliorates renal ischemia reperfusion injury in decay-accelerating factor and CD59 double knockout mice()

Complement is implicated in the pathogenesis of ischemia reperfusion injury (IRI). The activation pathway(s) and effectors(s) of complement in IRI may be organ-specific and remain to be fully characterized. We previously developed a renal IRI model in decay-accelerating factor (DAF) and CD59 double...

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Hlavní autoři: Miwa, Takashi, Sato, Sayaka, Gullipalli, Damodare, Nangaku, Masaomi, Song, Wen-Chao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608836/
https://ncbi.nlm.nih.gov/pubmed/23427256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202275
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