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Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammationand injury

Mechanical ventilation of lungs is capable of activating the innate immune system and inducing sterile inflammatory response. The proinflammatory cytokine IL-1β is among the definitive markers for accurately identifying ventilator-induced lung inflammation. However, mechanisms of IL-1β release durin...

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Autori principali: Wu, Jianbo, Yan, Zhibo, Schwartz, David E., Yu, Jingui, Malik, Asrar B., Hu, Guochang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608749/
https://ncbi.nlm.nih.gov/pubmed/23436933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200860
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