Odorant Metabolism Catalyzed by Olfactory Mucosal Enzymes Influences Peripheral Olfactory Responses in Rats

A large set of xenobiotic-metabolizing enzymes (XMEs), such as the cytochrome P450 monooxygenases (CYPs), esterases and transferases, are highly expressed in mammalian olfactory mucosa (OM). These enzymes are known to catalyze the biotransformation of exogenous compounds to facilitate elimination. H...

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Main Authors: Thiebaud, Nicolas, Veloso Da Silva, Stéphanie, Jakob, Ingrid, Sicard, Gilles, Chevalier, Joëlle, Ménétrier, Franck, Berdeaux, Olivier, Artur, Yves, Heydel, Jean-Marie, Le Bon, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608737/
https://ncbi.nlm.nih.gov/pubmed/23555703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059547
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