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Pmch-Deficiency in Rats Is Associated with Normal Adipocyte Differentiation and Lower Sympathetic Adipose Drive

The orexigenic neuropeptide melanin-concentrating hormone (MCH), a product of Pmch, is an important mediator of energy homeostasis. Pmch-deficient rodents are lean and smaller, characterized by lower food intake, body-, and fat mass. Pmch is expressed in hypothalamic neurons that ultimately are comp...

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Detalhes bibliográficos
Main Authors: Mul, Joram D., O’Duibhir, Eoghan, Shrestha, Yogendra B., Koppen, Arjen, Vargoviç, Peter, Toonen, Pim W., Zarebidaki, Eleen, Kvetnansky, Richard, Kalkhoven, Eric, Cuppen, Edwin, Bartness, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608591/
https://ncbi.nlm.nih.gov/pubmed/23555928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060214
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