White-Opaque Switching in Natural MTLa/α Isolates of Candida albicans: Evolutionary Implications for Roles in Host Adaptation, Pathogenesis, and Sex

Phenotypic transitions play critical roles in host adaptation, virulence, and sexual reproduction in pathogenic fungi. A minority of natural isolates of Candida albicans, which are homozygous at the mating type locus (MTL, a/a or α/α), are known to be able to switch between two distinct cell types:...

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Autors principals: Xie, Jing, Tao, Li, Nobile, Clarissa J., Tong, Yaojun, Guan, Guobo, Sun, Yuan, Cao, Chengjun, Hernday, Aaron D., Johnson, Alexander D., Zhang, Lixin, Bai, Feng-Yan, Huang, Guanghua
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608550/
https://ncbi.nlm.nih.gov/pubmed/23555196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001525
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