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Drug Resistant Breast Cancer Cell Line Displays Cancer Stem Cell Phenotype and Responds Sensitively to Epigenetic Drug SAHA

Cancer stem cell (CSC) population in solid human breast tumor was identified by CD44(+)/CD24(−) phenotype, characterized by high tumorigenicity, invasiveness and drug resistance. In this study, we characterized drug resistant breast cancer cell line-MCF-7/Adr and a number of breast cancer cell lines...

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Detalhes bibliográficos
Main Authors: Lu, Shan, Labhasetwar, Vinod
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608528/
https://ncbi.nlm.nih.gov/pubmed/23543868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-012-0113-z
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