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Response regulator–mediated MAPKKK heteromer promotes stress signaling to the Spc1 MAPK in fission yeast

The Spc1 mitogen-activated protein kinase (MAPK) cascade in fission yeast is activated by two MAPK kinase kinase (MAPKKK) paralogues, Wis4 and Win1, in response to multiple forms of environmental stress. Previous studies identified Mcs4, a “response regulator” protein that associates with the MAPKKK...

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Bibliographic Details
Main Authors: Morigasaki, Susumu, Ikner, Aminah, Tatebe, Hisashi, Shiozaki, Kazuhiro
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608495/
https://ncbi.nlm.nih.gov/pubmed/23389634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-10-0727
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