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The MAPT H1 haplotype is associated with tangle-predominant dementia
Tangle-predominant dementia (TPD) patients exhibit cognitive decline that is clinically similar to early to moderate-stage Alzheimer disease (AD), yet autopsy reveals neurofibrillary tangles in the medial temporal lobe composed of the microtubule-associated protein tau without significant amyloid-be...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3608475/ https://ncbi.nlm.nih.gov/pubmed/22802095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1017-1 |
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