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Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a kappa B-like sequence.

Using variable-length deletion constructs of the 5'-flanking region of the human interleukin-6 (IL-6) gene linked to the chloramphenicol acetyltransferase gene, we showed that the region from positions -109 to -50 mediated the bulk of the response to tumor necrosis factor (TNF) or interleukin-1...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Zhang, Y H, Lin, J X, Vilcek, J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360846/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2192263/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.7.3818
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