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Polymerization of a peptide-based enzyme substrate

Polymers of norbornenyl-modified peptide-based enzyme substrates have been prepared via ring-opening metathesis polymerization (ROMP). Peptides displayed on water-soluble homopolymers retain the ability to be enzymatically processed by a disease-associated enzyme. In contrast, when the peptides are...

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Detalhes bibliográficos
Main Authors: Hahn, Michael E., Randolph, Lyndsay M., Adamiak, Lisa, Thompson, Matthew P., Gianneschi, Nathan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608426/
https://ncbi.nlm.nih.gov/pubmed/23450132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc40472b
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