Amino Acid Derivatives as New Zinc Binding Groups for the Design of Selective Matrix Metalloproteinase Inhibitors

A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging from rheumatoid arthritis to cardiomyopathy, periodontal disease, liver cirrhosis, multiple sclerosis, and cancer invasion and metastasis, where they showed to have a dual role, inhibiting or promotin...

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Autori principali: Giustiniano, Mariateresa, Tortorella, Paolo, Agamennone, Mariangela, Di Pizio, Antonella, Rossello, Armando, Nuti, Elisa, Gomez-Monterrey, Isabel, Novellino, Ettore, Campiglia, Pietro, Vernieri, Ermelinda, Sala, Marina, Bertamino, Alessia, Carotenuto, Alfonso
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608355/
https://ncbi.nlm.nih.gov/pubmed/23555050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/178381
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