Tyrosine kinase activity is essential for the association of phospholipase C-gamma with the epidermal growth factor receptor.

Epidermal growth factor (EGF) treatment of NIH 3T3 cells transfected with wild-type EGF receptor induced tyrosine phosphorylation of phospholipase C-gamma (PLC-gamma). The EGF receptor and PLC-gamma were found to be physically associated such that antibodies directed against PLC-gamma or the EGF rec...

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Détails bibliographiques
Auteurs principaux: Margolis, B, Bellot, F, Honegger, A M, Ullrich, A, Schlessinger, J, Zilberstein, A
Format: Artigo
Langue:Inglês
Publié: 1990
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC360807/
https://ncbi.nlm.nih.gov/pubmed/2153914
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