The Design of Single-Arm Clinical Trials of Combination Antiretroviral Regimens for Treatment-Naive HIV-Infected Patients

Single-arm clinical trials are useful to evaluate antiretroviral regimens in certain populations of HIV-infected treatment-naive patients for whom a randomized controlled trial is not feasible or desirable. They can also be useful to establish initial estimates of efficacy and safety/tolerability of...

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Bibliographic Details
Main Authors: Zheng, Lu, Rosenkranz, Susan L., Taiwo, Babafemi, Para, Michael F., Eron, Joseph J., Hughes, Michael D.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2013
Subjects:
Clinical Trials/Clinical Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607972/
https://ncbi.nlm.nih.gov/pubmed/23228206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0180
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