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Hippocampal synaptic plasticity and spatial learning are impaired in a rat model of sleep fragmentation

Sleep fragmentation, a symptom in many clinical disorders, leads to cognitive impairments. To investigate the mechanisms by which sleep fragmentation results in memory impairments, rats were awakened once every 2 min via 30 s of slow movement on an automated treadmill. Within 1 h of this sleep inter...

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Autores principales: Tartar, Jaime L., Ward, Christopher P., McKenna, James T., Thakkar, Mahesh, Arrigoni, Elda, McCarley, Robert W., Brown, Ritchie E., Strecker, Robert E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607950/
https://ncbi.nlm.nih.gov/pubmed/16817877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2006.04808.x
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