Augmentation of Hepatitis B Virus-Specific Cellular Immunity with Programmed Death Receptor-1/Programmed Death Receptor-L1 Blockade in Hepatitis B Virus and HIV/Hepatitis B Virus Coinfected Patients Treated with Adefovir

The immunological parameters leading to viral persistence in chronic hepatitis B (CHB) are not clearly established. We analyzed HBV-specific immunoregulatory mechanisms in HIV-infected and HIV-uninfected HBeAg(+) CHB patients to determine (1) the roles of immunoregulatory pathways, (2) the effect of...

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Autori principali: Sherman, Amy C., Trehanpati, Nirupama, Daucher, Marybeth, Davey, Richard T., Masur, Henry, Sarin, Shiv Kumar, Kottilil, Shyam, Kohli, Anita
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2013
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607907/
https://ncbi.nlm.nih.gov/pubmed/23259453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0320
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