Llwytho...

Ca(2+) block and flickering both contribute to the negative slope of the IV curve in BK channels

Single-channel current–voltage (IV) curves of human large-conductance, voltage- and Ca(2+)-activated K(+) (BK) channels are quite linear in 150 mM KCl. In the presence of Ca(2+) and/or Mg(2+), they show a negative slope conductance at high positive potentials. This is generally explained by a Ca(2+)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schroeder, Indra, Thiel, Gerhard, Hansen, Ulf-Peter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607826/
https://ncbi.nlm.nih.gov/pubmed/23530139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210956
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