Protein Kinase G1 α Overexpression Increases Stem Cell Survival and Cardiac Function after Myocardial Infarction

BACKGROUND: We hypothesized that overexpression of cGMP-dependent protein kinase type 1α (PKG1α) could mimic the effect of tadalafil on the survival of bone marrow derived mesenchymal stem cells (MSCs) contributing to regeneration of the ischemic heart. METHODS AND RESULTS: MSCs from male rats were...

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Detalhes bibliográficos
Main Authors: Wang, Linlin, Pasha, Zeeshan, Wang, Shuyun, Li, Ning, Feng, Yuliang, Lu, Gang, Millard, Ronald W., Ashraf, Muhammad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607603/
https://ncbi.nlm.nih.gov/pubmed/23536905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060087
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