Protein Kinase G1 α Overexpression Increases Stem Cell Survival and Cardiac Function after Myocardial Infarction

BACKGROUND: We hypothesized that overexpression of cGMP-dependent protein kinase type 1α (PKG1α) could mimic the effect of tadalafil on the survival of bone marrow derived mesenchymal stem cells (MSCs) contributing to regeneration of the ischemic heart. METHODS AND RESULTS: MSCs from male rats were...

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Autori principali: Wang, Linlin, Pasha, Zeeshan, Wang, Shuyun, Li, Ning, Feng, Yuliang, Lu, Gang, Millard, Ronald W., Ashraf, Muhammad
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607603/
https://ncbi.nlm.nih.gov/pubmed/23536905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060087
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