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Possible Mechanical Roles of Glycosaminoglycans in Thoracic Aortic Dissection and Associations with Dysregulated TGF-β

BACKGROUND: Four distinguishing histopathological characteristics of thoracic aortic aneurysms and dissections (TAADs) are the fragmentation or degradation of elastic fibers, loss of smooth muscle, pooling of glycosaminoglycans, and remodeling of fibrillar collagens. Of these, pooling of glycosamino...

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Bibliografiske detaljer
Hovedforfatter: Humphrey, J.D.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607504/
https://ncbi.nlm.nih.gov/pubmed/23018968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000342436
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