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Inactivation of the cellular p53 gene is a common feature of Friend virus-induced erythroleukemia: relationship of inactivation to dominant transforming alleles.

The Friend erythroleukemia virus complex contains no cell-derived oncogene. Transformation by this virus may therefore involve mutations affecting cellular gene expression. We provide evidence that inactivating mutations of the cellular p53 gene are a common feature in Friend virus-induced malignanc...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Munroe, D G, Peacock, J W, Benchimol, S
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360748/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1694008/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.7.3307-3313.1990
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