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AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
Overcoming metabolic stress is a critical step for solid tumour growth(1,2). However, the underlying mechanisms of cell death and survival under metabolic stress are not well understood. A key signalling pathway involved in metabolic adaptation is the liver kinase B1 (LKB1)–AMP-activated protein kin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607316/ https://ncbi.nlm.nih.gov/pubmed/22660331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11066 |
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