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E1a transactivation of human HSP70 gene promoter substitution mutants is independent of the composition of upstream and TATA elements.

We have analyzed 41 deletion, linker scan, and substitution mutants of the human HSP70 gene promoter for activation by the adenovirus E1a region. No natural element of the HSP70 gene promoter was required for activation. To investigate specific interactions between E1a and transcription factors, a s...

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Autori principali: Taylor, I C, Kingston, R E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC360725/
https://ncbi.nlm.nih.gov/pubmed/2152962
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