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Two Mechanisms Produce Mutation Hotspots at DNA Breaks in Escherichia coli
Mutation hotspots and showers occur across phylogeny and profoundly influence genome evolution, yet the mechanisms that produce hotspots remain obscure. We report that DNA double-strand breaks (DSBs) provoke mutation hotspots via stress-induced mutation in Escherichia coli. With tet reporters placed...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cell Press
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607216/ https://ncbi.nlm.nih.gov/pubmed/23041320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.08.033 |
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