AMP-activated protein kinase is required for exercise-induced peroxisome proliferator-activated receptor γ co-activator 1α translocation to subsarcolemmal mitochondria in skeletal muscle

In skeletal muscle, mitochondria exist as two subcellular populations known as subsarcolemmal (SS) and intermyofibrillar (IMF) mitochondria. SS mitochondria preferentially respond to exercise training, suggesting divergent transcriptional control of the mitochondrial genomes. The transcriptional co-...

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Autors principals: Smith, Brennan K, Mukai, Kazutaka, Lally, James S, Maher, Amy C, Gurd, Brendon J, Heigenhauser, George J F, Spriet, Lawrence L, Holloway, Graham P
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2013
Matèries:
Skeletal Muscle and Exercise
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607172/
https://ncbi.nlm.nih.gov/pubmed/23297307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.245944
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