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A naturally occurring gamma globin gene mutation enhances SP1 binding activity.

Transcription of the human fetal globin genes in erythroid cells is tightly regulated during different stages of development and differentiation. Two naturally occurring mutations 202 base pairs upstream of the duplicated gamma globin genes are associated with incorrectly regulated gamma globin gene...

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Hlavní autoři: Sykes, K, Kaufman, R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC360716/
https://ncbi.nlm.nih.gov/pubmed/1688466
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