Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease

Cerebral dopamine neurotrophic factor (CDNF) protein has been shown to protect the nigrostriatal dopaminergic pathway when given as intrastriatal infusions in rat and mouse models of Parkinson's disease (PD). In this study, we assessed the neuroprotective effect of CDNF delivered with a recombi...

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Detaylı Bibliyografya
Asıl Yazarlar: Bäck, Susanne, Peränen, Johan, Galli, Emilia, Pulkkila, Päivi, Lonka-Nevalaita, Liina, Tamminen, Tuulia, Voutilainen, Merja H, Raasmaja, Atso, Saarma, Mart, Männistö, Pekka T, Tuominen, Raimo K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2013
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607149/
https://ncbi.nlm.nih.gov/pubmed/23532969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.117
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