Induction of differentiation in v-Ha-ras-transformed MDCK cells by prostaglandin E2 and 8-bromo-cyclic AMP is associated with a decrease in steady-state level of inositol 1,4,5-trisphosphate.

We used Ha-ras-transformed Madin-Darby canine kidney (MDCK) cells as a model to study possible signal transduction mechanisms underlying the induction of glucagon responsiveness by the differentiation inducers prostaglandin E2 (PGE2) and 8-bromo-cyclic (8-Br-cAMP) AMP and the inhibition of induction...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Wu, Y Y, Lin, M C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360712/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2152966/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.1.57-67.1990
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