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Arf tumor suppressor and miR-205 regulate cell adhesion and formation of extraembryonic endoderm from pluripotent stem cells

Induction of the Arf tumor suppressor (encoded by the alternate reading frame of the Cdkn2a locus) following oncogene activation engages a p53-dependent transcriptional program that limits the expansion of incipient cancer cells. Although the p19(Arf) protein is not detected in most tissues of fetal...

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Autori principali: Li, Chunliang, Finkelstein, David, Sherr, Charles J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607049/
https://ncbi.nlm.nih.gov/pubmed/23487795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302184110
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