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Arf tumor suppressor and miR-205 regulate cell adhesion and formation of extraembryonic endoderm from pluripotent stem cells

Induction of the Arf tumor suppressor (encoded by the alternate reading frame of the Cdkn2a locus) following oncogene activation engages a p53-dependent transcriptional program that limits the expansion of incipient cancer cells. Although the p19(Arf) protein is not detected in most tissues of fetal...

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Autors principals: Li, Chunliang, Finkelstein, David, Sherr, Charles J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607049/
https://ncbi.nlm.nih.gov/pubmed/23487795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302184110
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