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Estrogen receptor β sustains epithelial differentiation by regulating prolyl hydroxylase 2 transcription

Estrogen receptor β (ERβ) promotes the degradation of hypoxia inducible factor 1α (HIF-1α), which contributes to the ability of this hormone receptor to sustain the differentiation of epithelial and carcinoma cells. Although the loss of ERβ and consequent HIF-1 activation occur in prostate cancer wi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mak, Paul, Chang, Cheng, Pursell, Bryan, Mercurio, Arthur M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607009/
https://ncbi.nlm.nih.gov/pubmed/23487784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221654110
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