Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB(1) receptor blockade

Complex interactions between periphery and the brain regulate food intake in mammals. Cannabinoid type-1 (CB(1)) receptor antagonists are potent hypophagic agents, but the sites where this acute action is exerted and the underlying mechanisms are not fully elucidated. To dissect the mechanisms under...

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Main Authors: Bellocchio, Luigi, Soria-Gómez, Edgar, Quarta, Carmelo, Metna-Laurent, Mathilde, Cardinal, Pierre, Binder, Elke, Cannich, Astrid, Delamarre, Anna, Häring, Martin, Martín-Fontecha, Mar, Vega, David, Leste-Lasserre, Thierry, Bartsch, Dusan, Monory, Krisztina, Lutz, Beat, Chaouloff, Francis, Pagotto, Uberto, Guzman, Manuel, Cota, Daniela, Marsicano, Giovanni
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607008/
https://ncbi.nlm.nih.gov/pubmed/23487769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218573110
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