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Analysis of Time-to-Event and Duration Outcomes in Neonatal Clinical Trials with Twin Births
When conducting neonatal trials in pre-term and/or low-birth-weight infants, twins may represent 10–20% of the study sample. Frailty models and proportional hazards regression with a robust sandwich variance estimate are common approaches for handling correlated time-to-event data or duration outcom...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606884/ https://ncbi.nlm.nih.gov/pubmed/19027881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2008.11.001 |
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