Necrotising enterocolitis is characterised by disrupted immune regulation and diminished mucosal regulatory (FOXP3)/effector (CD4, CD8) T cell ratios

BACKGROUND: Necrotising enterocolitis (NEC) is the most common gastrointestinal emergency in premature infants. Immaturity of gastrointestinal immune regulation may predispose preterm infants to NEC as FOXP3 T regulatory cells (Treg) are critical for intestinal immune homoeostasis. OBJECTIVE: To inv...

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Main Authors: Weitkamp, Jörn-Hendrik, Koyama, Tatsuki, Rock, Michael T, Correa, Hernan, Goettel, Jeremy A, Matta, Pranathi, Oswald-Richter, Kyra, Rosen, Michael J, Engelhardt, Brian G, Moore, Daniel J, Polk, D Brent
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606820/
https://ncbi.nlm.nih.gov/pubmed/22267598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2011-301551
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