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A novel hepatitis B vaccine containing Advax™, a polysaccharide adjuvant derived from delta inulin, induces robust humoral and cellular immunity with minimal reactogenicity in preclinical testing

Although current HBV vaccines have an outstanding record of safety and efficacy, reduced immunogenicity is a problem in those of older age, or having renal impairment or diabetes mellitus. In this study, we tested the ability of Advax™ adjuvant, a novel polysaccharide adjuvant based on delta inulin,...

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Detalhes bibliográficos
Main Authors: Saade, Fadi, Honda-Okubo, Yoshikazu, Trec, Samay, Petrovsky, Nikolai
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606636/
https://ncbi.nlm.nih.gov/pubmed/23306367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.12.077
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