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Crystallization and X-ray crystallographic analysis of the cap-binding domain of influenza A virus H1N1 polymerase subunit PB2

PB2 is one of the subunits of the influenza virus heterotrimeric polymerase. By its cap-binding domain (PB2(cap)), PB2 captures the 5′ cap of the host pre-mRNA to generate a capped 5′ oligonucleotide primer for virus transcription. The crystal structure of influenza A virus H3N2 PB2(cap) with bound...

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Detalhes bibliográficos
Main Authors: Liu, Yong, Meng, Geng, Luo, Ming, Zheng, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606574/
https://ncbi.nlm.nih.gov/pubmed/23519804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113002388
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