Iron loading impairs lipoprotein lipase activity and promotes hypertriglyceridemia

Iron loading is associated with altered lipid metabolism, but underlying mechanisms remain unknown. We compared serum iron and triglycerides (TGs) in Belgrade rats, a genetic model of iron-loading anemia. Homozygous b/b rats had greater serum iron (68 vs. 28 μM; P=0.0004) and TG levels (180 vs. 84 m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, Jonghan, Jia, Xuming, Buckett, Peter D., Liu, Sihao, Lee, Chih-Hao, Wessling-Resnick, Marianne
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Federation of American Societies for Experimental Biology 2013
Pynciau:
Research Communications
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606537/
https://ncbi.nlm.nih.gov/pubmed/23241313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-224386
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