Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis

MicroRNA cluster miR-17-92 has been implicated in cardiovascular development and function, yet its precise mechanisms of action in these contexts are uncertain. This study aimed to investigate the role of miR-17-92 in morphogenesis and function of cardiac and smooth muscle tissues. To do so, a mouse...

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Hlavní autoři: Danielson, Laura S., Park, David S., Rotllan, Noemi, Chamorro-Jorganes, Aranzazu, Guijarro, Maria V., Fernandez-Hernando, Carlos, Fishman, Glenn I., Phoon, Colin K. L., Hernando, Eva
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2013
Témata:
Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606524/
https://ncbi.nlm.nih.gov/pubmed/23271053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-221994
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