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Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles

BACKGROUND: In the mouse ovary, oocytes initially develop in clusters termed germ-cell nests. Shortly after birth, these germ-cell nests break apart, and the oocytes individually become surrounded by somatic granulosa cells to form primordial follicles. Notch signaling plays essential roles during o...

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מידע ביבליוגרפי
Main Authors: Xu, Jingxia, Gridley, Thomas
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606475/
https://ncbi.nlm.nih.gov/pubmed/23406467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-11-13
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