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Activation of the proto-oncogene p60c-src by point mutations in the SH2 domain.

To investigate the importance of a conserved region spanning residues 137 to 241 in the noncatalytic domain of p60c-src (SH2 region), we used oligonucleotide-directed mutagenesis to change residues that are highly conserved in this region. Chicken embryo fibroblasts infected with a p60c-src variant...

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Publicat a:Mol Cell Biol
Autors principals: O'Brien, M C, Fukui, Y, Hanafusa, H
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360647/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2111444/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.6.2855
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